What is rheumatoid factor




















One blood test measures levels of rheumatoid factors in the blood. Rheumatoid factors are proteins that the immune system produces when it attacks health tissue. About half of all people with rheumatoid arthritis have high levels of rheumatoid factors in their blood when the disease starts, but about 1 in 20 people without rheumatoid arthritis also test positive.

A related blood test known as anti-cyclic citrullinated peptide anti-CCP test is also available. Anti-CCPs are antibodies also produced by the immune system. People who test positive for anti-CCP are very likely to develop rheumatoid arthritis, but not everybody with rheumatoid arthritis has this antibody. Those who test positive for both rheumatoid factor and anti-CCP may be more likely to have severe rheumatoid arthritis requiring higher levels of treatment. This may help to reduce inflammation.

Canes and crutches can help you maintain mobility, even during flares. You can also install household devices, such as grab bars and handrails in bathrooms and along staircases. Learn more about these and other remedies to help you manage life with RA. Your healthcare provider or dietitian may recommend an anti-inflammatory diet to help with your symptoms. This type of diet includes foods that have lots of omega-3 fatty acids. Foods high in omega-3 fatty acids include:.

Antioxidants, such as vitamins A , C , and E , and selenium , may also help reduce inflammation. Foods high in antioxidants include:. Eating lots of fiber is also important. According to some researchers, fiber may help reduce inflammatory responses which may decrease C-reactive protein levels.

Choose whole grain foods, fresh vegetables, and fresh fruit. Strawberries may be particularly beneficial. Foods containing flavonoids can also help to counter inflammation in the body. They include:. Make sure to avoid trigger foods. These include processed carbohydrates and saturated or trans fats.

Avoiding trigger foods and choosing the right foods in trying to follow an anti-inflammatory diet may help you manage your RA. There are several different types of RA. Knowing which type you have may help your healthcare provider provide the best type of treatment for you. Get more details on the types of RA and their differences.

Seropositive RA is the most common type of RA. This type of arthritis may run in families. Seropositive RA may come with more severe symptoms than seronegative RA. Some people with seropositive RA can experience inflammation in the eyes, salivary glands, nerves, kidneys, lungs, heart, skin, and blood vessels. However, certain factors seem to play a role in increasing the risk of developing RA or triggering its onset.

The cause may not be known but there are several risks and triggers. Arthritis in the hands may start as a low-level burning sensation that you feel at the end of the day.

If the cartilage in your joints wears away, you may notice some deformities in your hands. You may also have a grinding feeling in the joints of your hands, fingers, and large joints, if the cartilage deteriorates completely.

As the disease progresses, fluid-filled sacs or synovial cysts typically develop in the wrists, knees, elbows, ankles and around the small joints of the hands. You may also develop knobby growths, called bone spurs, in the affected joints.

Over time, bone spurs can make it harder for you to use your hands. If you have RA in your hands, your healthcare provider will work with you on exercises that can help you retain movement and function. Exercises, along with other types of treatment, can help reduce inflammation and stave off progression of the disease. See exactly what the effects of RA looks like on your hands. Swelling of fingers, wrists, knees, ankles, and toes are common. Both tests are used to test disease activity; when they are high, this suggests that the disease is very active assuming no other causes for high results, such as infection, are present.

A complete blood count CBC test looks at red and white blood cell counts. Below are the normal measurements in our lab — other labs may well have their own set of normal values.

The CBC tests help to inform the healthcare team about side effects of treatment and any secondary consequences of RA, such as anemia. A complete metabolic panel is used to monitor kidney and liver function, in order to assess whether changes to medication must be made or whether they are working well. A complete metabolic panel measures sodium Na , potassium K , chloride, glucose, creatinine a measure of kidney function , and AST and ALT markers of liver function.

Both the CBC and the complete metabolic panel are used to monitor disease activity as well as side effects and efficacy of medication. Laboratory tests provide important information in the diagnosis, management and treatment of rheumatoid arthritis. By becoming informed about the normal values for tests, as well as their own numbers, patients with RA can better communicate with the health care team and gain a better understanding about some of the information that is used in developing and monitoring their treatment plans.

The results of these tests may be used in two ways: To confirm the presence of the RA. To determine how active the disease is.

After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes. There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.

About 20 percent of people with rheumatoid arthritis have little or no rheumatoid factor in their blood. So even if your results were normal, your health care provider may order more tests to confirm or rule out a diagnosis.

If your results were not normal, it doesn't necessarily mean you have a medical condition needing treatment. Some healthy people have rheumatoid factor in their blood, but it's not clear why. Learn more about laboratory tests, reference ranges, and understanding results. An RF test is not used to diagnose osteoarthritis. Although rheumatoid arthritis and osteoarthritis both affect the joints, they are very different diseases.

Rheumatoid arthritis is an autoimmune disease that affects people at any age, but usually occurs between the ages of 40 and



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