Flexeril 5 mg is comparable in efficacy to the 10 mg strength, but has been shown to be significantly less sedating. Clinical research has demonstrated that doses of cyclobenzaprine lower than 5 mg are not effective for the treatment of acute painful muscle spasm of the back or neck. Cyclobenzaprine HCl 10 mg tablets are not designed for splitting tablets studied were film coated and unscored , so there is an increased likelihood that they will split unevenly, crumble or shatter,? Splitting unscored tablets to yield partial doses of a medication can result in uneven splitting that may, in turn, lead to dosing errors and variable efficacy and safety of the medication.?
The National Association of Boards of Pharmacy adopted a resolution in opposing mandated tablet splitting, describing the practice as? The American Pharmacists Association APhA and the American Medical Association AMA have also stated that they formally oppose mandatory tablet splitting, and the APhA Strategic Directions Committee recently proposed a practice tool to help pharmacists evaluate the appropriateness of tablet splitting in certain patient or product scenarios.
These considerations and the results of the current study strongly suggest that generic cyclobenzaprine HCl 10 mg tablets should not be cut in half,? Cook, an Assistant Professor of Pharmaceutics and a licensed pharmacist, and two fourth-year Doctor of Pharmacy students at Rutgers?
Ernest Mario School of Pharmacy conducted the study, which evaluated the weight variability of 90 cyclobenzaprine HCl 10 mg tablets. Since generic cyclobenzaprine HCl 10 mg tablets are not designed for splitting tablets are not scored , there is an increased likelihood that they will split unevenly, crumble or shatter, according to Dr. The best way to be confident that a patient consistently gets the intended amount of medication is to take the 5 mg tablet as prescribed.
About the Study Dr. Cook, a licensed pharmacist, and two fourth-year PharmD students at the Ernest Mario School of Pharmacy conducted the study, which evaluated the weight variability of 90 cyclobenzaprine HCl 10 mg tablets. Conclusion: Tablet fragments obtained after splitting this generic cyclobenzaprine 10 mg product varied considerably in weight and estimated drug content. Accordingly, splitting cyclobenzaprine 10 mg tablets to achieve 5 mg doses could result in unpredictable dosing and therapeutic response.
Abstract Objective: To determine the weight variation and calculated dosing variability of tablet fragments upon splitting unscored cyclobenzaprine hydrochloride 10 mg tablets using two common tablet splitting devices.
The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects. Your doctor may start you on a lowered dose or a different dosing schedule. This can help keep levels of this drug from building up too much in your body. For people with liver problems: If your liver problems are mild, your doctor may start you on a lowered dose or a different dosing schedule.
However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you. Cyclobenzaprine oral tablet is used for short-term treatment. You may have more muscle spasms or pain.
For this drug to work well, a certain amount needs to be in your body at all times. If you take too much: You could have dangerous levels of the drug in your body.
Symptoms of an overdose of this drug can include:. If your symptoms are severe, call or go to the nearest emergency room right away. What to do if you miss a dose: Take your dose as soon as you remember.
But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects. How to tell if the drug is working: You should have less muscle pain and stiffness. As with all medications, the costs of cyclobenzaprine can vary.
To find current prices for your area, check out GoodRx. A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled.
Your doctor will write the number of refills authorized on your prescription. If you have liver problems, you doctor may do a blood test to monitor how well your liver is working while you take this drug. Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription.
There are other drugs available to treat your condition. Some may be better suited for you than others.
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